the most versatile
sCMOS camera portfolio
on the market
on the cutting edge
edge 4. 2 LT
edge 3. 1 &
layers—and those of the retinal pigment
epithelium, as well as the vessels of the
choroid. But by simply changing the focal
position, it is also possible to image the
cornea, sclera, and conjunctiva with no
increase in optical power. Indications for
clinical use include the evaluation of ophthalmic tissue in routine clinical examinations and as an aid in the diagnosis of conditions that affect the optical scattering
properties of ocular tissue (see Frontis).
This sophisticated OCT hardware and
software system enables real-time noninvasive imaging of internal tissue microstructure, extending the SD-OCT application space to include imaging of patients
throughout the clinical environment and
imaging a wide range of animal subjects.
It is ideally suited to image the retina in
small animals (rodents, rabbits), large animals (such as dogs and pigs), and humans.
The SDOIS, which received FDA clearance 510(k) in 2006, includes a handheld
probe and a microscope setup. The axial
resolution is 5 μm and A-scan acquisition
rate is 27 kHz. 1 The device was adapted
on a binocular indirect ophthalmolo
Optovue’s SDOCT-based iVue offers complete retina, glaucoma (including ganglion cell complex analysis), and anterior
segment scanning. It received clearance
by the FDA through a 510(k) procedure
in 2009. Axial resolution is 5 μm; A-scan
acquisition rate is 27 kHz.
OCT camera by OPmed T
OptoMedical Technologies GMBH
(OPmedT; Lubeck, Germany) has
developed an OCT camera that can be
mounted on a surgical microscope, the
Hi-R 900 by Möller-Wedel GmbH. The
camera can be used to visualize the anterior and posterior segment of the eye, and
OPmedT indicates the following surgical applications: corneal transplantation
(including lamellar keratoplasties), glaucoma surgery, cataract surgery, and retinal surgery (e.g., ILM peeling).
3D-OCT 2000 by Topcon
Topcon’s 3D-OCT 2000 incorporates
SD-OCT and a high-resolution fundus
camera. Axial resolution is 5 μm; A-scan
acquisition rate is 27 kHz.
SOCT Copernicus by Optopol
Optopol’s SOCT Copernicus includes
progression analysis software that calculates disc damage likelihood, symmetry
between the disc, and retinal nerve fiber
layer (RNFL) thickness. Axial resolution
is 6 μm; A-scan acquisition rate is 27 kHz.
Spectral OCT SLO by Optko
Optko’s device combines SD-OCT, scanning laser ophthalmology (SLO), and
microperimetry. Axial resolution is 6 μm;
A-scan acquisition rate is 27 kHz.
Spectralis OCT by Heidelberg
Heidelberg Engineering’s Spectralis
includes a high-speed SD-OCT system
with eye tracking, fluorescein angiography, ICG angiography, and autofluores-cence. Axial resolution is 4 μm; A-scan
acquisition rate is 40 kHz.
Cirrus HD OCT and OPMI VISU
200 by Carl Zeiss Meditec
FIGURE 1. Bioptigen’s Envisu is a spectral-domain
OCT (SD-OCT) system. The company has received a
$1.72 million grant for development of microscope-integrated intraoperative OCT technology.